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Cochrane Clinical Answers

What are the effects of lutein and zeaxanthin supplementation in preterm infants in neonatal intensive care units (NICUs)?

Ashraf Nabhan, Nermin Hassan
16 October 2025

What are the effects of progestogen for preventing miscarriage in individuals with a history of recurrent miscarriage of unclear etiology?

Selena Ryan‐Vig, Agustín Ciapponi
16 October 2025

For adults with presumed early‐stage endometrial cancer, what are the benefits and risks of performing pelvic lymphadenectomy at the time of standard surgery (typically hysterectomy and bilateral salpingo‐oophorectomy) versus standard surgery alone?

Ashraf Nabhan, Sara Ibrahim Abdelkader
15 October 2025

In adults with premenstrual syndrome (PMS), what are the benefits and risks of gonadotropin‐releasing hormone (GnRH) agonist treatment (without additional estrogen or progestogen)?

Amin Sharifan
23 September 2025

For adults undergoing rehabilitation at varying time periods following stroke, what are the benefits and harms of virtual reality, either compared to alternative therapeutic approaches or added to usual care?

Selena Ryan‐Vig, Ahmed Samir
23 September 2025

What are the effects of endovascular thrombectomy with or without intravenous thrombolysis (IVT) in adults with acute ischemic stroke?

KoKo Aung
9 September 2025

In adults with osteoarthritis of the knee, how do stem cell injections compare with hyaluronic acid injections?

Ashraf Nabhan, Ahmed Saied
9 September 2025

In adults with osteoarthritis of the knee, how do stem cell injections compare with placebo injections?

Ashraf Nabhan, Seif Yasser
9 September 2025

In adults undergoing neuraxial anesthesia, how does ultrasound guidance compare with anatomical landmarks?

Agustín Ciapponi
9 September 2025

For adults with inflammatory bowel disease (IBD), what are the effects of psychotherapy, educational interventions, and relaxation techniques compared with usual care?

Sarah El‐Nakeep
2 September 2025

In adults with chronic heart failure in sinus rhythm, how does anticoagulation (warfarin) compare with antiplatelets (aspirin or clopidogrel) in terms of all‐cause mortality, non‐fatal cardiovascular events, and major bleeding?

Selena Ryan‐Vig, Agustín Ciapponi
2 September 2025

What are the benefits and risks of different surgical and conversative treatments for adults with ulnar neuropathy at the elbow?

David S. Edwards
30 August 2025

What are the benefits and risks of corticosteroids for treating people with sepsis?

Selena Ryan‐Vig, Husein Husein‐ElAhmed
28 August 2025

What are the effects of standalone clinical pathways on patient outcomes, length of stay, hospital costs, and adherence to recommended practice across diverse patient populations and clinical settings?

Ashraf Nabhan, Sara Ibrahim Abdelkader
28 August 2025

During primary surgical repair of congenital esophageal atresia with tracheoesophageal fistula in newborns, how does preservation versus ligation of the azygos vein compare?

Nai Ming Lai
26 August 2025

What are the effects of home‐based educational interventions for children with asthma?

Elie Mulhem
26 August 2025

What are the effects of alternative models of care for people with acute or chronic non‐specific low back pain?

Jaimo Ahn
26 August 2025

What are the effects of psychosocial breastfeeding support interventions for preventing postpartum depression?

Ashraf Nabhan, Sara Ibrahim Abdelkader
26 August 2025

How do renin inhibitors compare with angiotensin receptor blockers (ARBs) for adults with primary hypertension?

KoKo Aung
24 August 2025

What are the benefits and harms of typhoid conjugate vaccines for the prevention of typhoid fever?

Smitha Bhat
22 August 2025

For adults with completely resected stage II to III non‐small cell lung cancer (NSCLC) and epidermal growth factor receptor (EGFR) mutation, how do adjuvant EGFR tyrosine kinase inhibitors (TKIs) compare with standard platinum‐based adjuvant chemotherapy?

Amin Sharifan
22 August 2025

For adult kidney transplant recipients at high risk of delayed graft function, how does delayed initiation of calcineurin inhibitors (CNI) compare with early initiation?

Samira Bell
20 August 2025

For adult kidney transplant recipients at high risk of delayed graft function, how does a low dose of calcineurin inhibitors (CNI) compare with a higher dose?

Samira Bell
20 August 2025

In adults after stroke, how does electromechanical‐ or robot‐assisted gait training compare with physiotherapy or usual care in improving walking outcomes?

Selena Ryan‐Vig, Husein Husein‐ElAhmed
20 August 2025

For people with postpartum iron deficiency anemia, how does treatment with intravenous (IV) iron compare with oral iron?

George Daskalakis
13 August 2025